Sunday, December 04, 2011

Canadians Reverse Alzheimer's Memory Loss

So, is Alzheimer's one disease, or two different diseases? It seems that the Canadians have reversed Alheimer's memory loss via deep brain stimulation. This suggests that some Alzheimer's patients are possibly curable with this technique.

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This deep brain approach might have unstated origins in http://en.wikipedia.org/wiki/Electroconvulsive_therapy (ECT). With ECT now using small targeted bursts of electicity - nothing like one flew over the cuckoo's nest.
 
John

Have a tranquil Christmas and a triumphant New Year.

Your friend Pete
 
There is a is a blood stem cell growth factor or hormone that reversed memory impairment. Injection of GCSF compound, under the skin, mobilized blood stem cells in bone marrow and neural stem cells within the brain, decreasing amyloid plaque burden and improving learning behavior. GCSF is in FDA clinical trials to treat stroke.
 
Apparently, taking Targetrin which is an anticancer drug stimulates apolipoprotein E4 production which removes plaques from the brain and reverses the disease. That jives nicely with earlier research (15 years ago) that showed that a specific mutation in the gene that makes apolipoprotein E4 could result in early onset of Alzheimer's disease.
 
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