Sunday, July 06, 2008

Resveratrol and Vitamins

I haven't written much lately regarding medical matters. There is some new research confirming that one of several beneficial compounds stimulated gene expression and retards age related physiological declines. The links are here and here. It portends a long quality of life for some of us. You need not wait for the pill, just drink grape juice or red wine. You won't live longer, but you'll live better. This latest news is just confirmation of previous research. If you start caloric restriction, you'll get 20-30% longer life, but most people can't handle the diet, so this is the next best thing.

Another study found that a small fraction of the population have one or more enzyme variants that misfold and do not function. However, when supplements such as vitamins were added, the enzymes folded properly and functioned. In this case, the vitamin wasn't just a coenzyme. It is acting as a scaffold or mold to help the protein fold into its proper 3 dimensional shape so that it will work. This is a case where phenotype masks genotype. It's due to a conditional mutation which affects protein folding. The reason why it's not serious is because without the specific vitamin (an environmental factor), the enzyme wouldn't work any way even if it were properly folded and otherwise functional. What it means though, is that certain people have higher dietary vitamin requirements than others.

Here's to the grape! Cheers!


Finally the media caught up the scientific studies of a drink I have been using for more than 7 years, if I am aloud to say the name it is symmetry direct genesis one of the highest standardized Resveratrol non-alcoholic drink. You can understand my excitement when I saw the media started to report their Resveratrol findings. Let’s hope more Doctors start looking in this direction. By the way I look and feel a lot younger than 47 and I intend to keep it that way. Note we will hear a lot more about the combination of Two Miracle Molecules: Ellagic Acid and Resveratrol.
There is no miracle here. Just less ignorance and more information. Resveratrol is backed up by extensive studies and peer reviewed research. The jury is out on ellagic acid. There's little data verifying its antioxidant protective effects. Longevity studies is a very young field of research, less than 20 years old, and it's politcally driven by elderly politicians who wish to remain in power as long as possible. Also, evolution favors reproduction over longevity. The longer you live, the less fecund you are, and the greater the chance that your population could be wiped out by predators or illness.
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