Monday, August 27, 2007

Progress in Preventative Medical Research

There has been much progress made in preventative medicine of late. A Warwick University team discovered that people with Type I and II diabetes have a severe thiamine deficiency. They had to use a new blood test to determine this result because the old test indicated the opposite result. If one looks at the symptoms of beriberi, you'll find that sufferers have peripheral nerve and heart damage similar to the damage caused by diabetes.

A group at The University of San Diego Medical Center have shown an inverse relationship between serum blood levels of vitamin D and cancer rates. The lower the blood levels of vitamin D, the higher the incidence of common cancers. This may explain why night shift workers have twice the cancer rate of most people and why blacks have poorer survival rates of cancer treatments in Northern countries. They recommend 2000 IU of vitamin D daily along with 15 minutes exposure to the sun. It turns out that vitamin D is the only vitamin that is converted to a hormone. It alters mood and is probably the reason for seasonal depression and the addiction to tanning beds, though I've seen no studies yet.

There's also a study showing that you have to take a lot of vitamin E to get any benefit, about 1600 IU. Previous clinical trials weren't measuring any clinical biochemical markers, just testing for an absence of disease effects. So, they were poorly designed studies.

Another study has explained why a caloric restriction diet works. Fasting or a restricted diet stimulates cells to catabolize (eat) damaged organelles and cellular components such as proteins, fats, and such, and produce new replacements. Since damaged mitochondria are responsible for Type II diabetes and its memory effects, with caloric restriction, it should be possible to reverse Type II diabetes in people. Indeed, caloric restriction's molecular mechanism explains why people with gastric bypasses experience Type II diabetes remission. Resveratrol may stimulate the same molecular pathways as caloric restriction does as well as prevent cellular damage due to its antioxidant effect.


Interesting especially about the caloric restriction diet. One more reason for me to cut my calories. I was watching a program on TV the other day and this doctor was talking about the benefits of vitamin D and Folate, or folic acid. Our diets our deficient in these important vitamins.

Good stuff here, Thanks!
Excellent summary. Thanks!
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